International Journal of Infection

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Hepatitis A Infection Presented with Pancytopenia, a Case Series in Children

Majid Naderi 1 , Iraj Shahramian 2 , * , Ali Bazi ORCID 3 , Mojtaba Delaramnasab 3 and Gholamreza Kalvandi 4
Authors Information
1 Genetics of Non-Communicable Disease Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
2 Pediatric Digestive and Hepatic Research Center, Zabol University of Medical Sciences, Zabol, Iran
3 Faculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, Iran
4 Department of Pediatrics and Medicine, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
Article information
  • International Journal of Infection: 6 (1); e87332
  • Published Online: January 27, 2019
  • Article Type: Case Report
  • Received: December 11, 2018
  • Revised: December 28, 2018
  • Accepted: January 5, 2019
  • DOI: 10.5812/iji.87332

To Cite: Naderi M, Shahramian I, Bazi A, Delaramnasab M, Kalvandi G. Hepatitis A Infection Presented with Pancytopenia, a Case Series in Children, Int J Infect. Online ahead of Print ; 6(1):e87332. doi: 10.5812/iji.87332.

Abstract
Copyright © 2019, International Journal of Infection. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Results
4. Discussion
Footnotes
References
  • 1. Bhatt G, Sandhu VS, Mitchell CK. A rare presentation of hepatitis a infection with extrahepatic manifestations. Case Rep Gastrointest Med. 2014;2014:286914. doi: 10.1155/2014/286914. [PubMed: 25295197]. [PubMed Central: PMC4177781].
  • 2. Shahramian I, Rostami D, Sharafi E, Sargazi-aval O, Delaramnasab M, Bazi A. Serological and biochemical study of hepatitis B patients, a report from the southeast of Iran. Future Virol. 2018;13(2):103-10. doi: 10.2217/fvl-2017-0102.
  • 3. Das S, Chatterjee A, Bhattacharya M, Basu S, Bhakta S, Kundu S, et al. Aseptic meningitis and infection-associated hemophagocytic lymphohistiocytosis-rare complications of hepatitis a virus infection. J Pediatr Infect Dis. 2016;11(4):136-40. doi: 10.1055/s-0036-1597924.
  • 4. Willner IR, Uhl MD, Howard SC, Williams EQ, Riely CA, Waters B. Serious hepatitis A: An analysis of patients hospitalized during an urban epidemic in the United States. Ann Intern Med. 1998;128(2):111-4. doi: 10.7326/0003-4819-128-2-199801150-00006. [PubMed: 9441570].
  • 5. Cuthbert JA. Hepatitis A: Old and new. Clin Microbiol Rev. 2001;14(1):38-58. doi: 10.1128/CMR.14.1.38-58.2001. [PubMed: 11148002]. [PubMed Central: PMC88961].
  • 6. Hajibeigi B, Azarkeivan A, Nasiritosi M. Interferon alpha and pancytopenia in a thalassemic patient who treating for HCV; Cause of death. Hepat Mon. 2011;11(1):37.
  • 7. Pol S, Thiers V, Driss F, Devergie A, Berthelot P, Brechot C, et al. Lack of evidence for a role of HCV in hepatitis-associated aplastic anaemia. Br J Haematol. 1993;85(4):808-10. doi: 10.1111/j.1365-2141.1993.tb03229.x. [PubMed: 7918049].
  • 8. Safadi R, Or R, Ilan Y, Naparstek E, Nagler A, Klein A, et al. Lack of known hepatitis virus in hepatitis-associated aplastic anemia and outcome after bone marrow transplantation. Bone Marrow Transplant. 2001;27(2):183-90. doi: 10.1038/sj.bmt.1702749. [PubMed: 11281388].
  • 9. Riaz Shah SA, Idrees M, Hussain A. Hepatitis G virus associated aplastic anemia: A recent case from Pakistan. Virol J. 2011;8:30. doi: 10.1186/1743-422X-8-30. [PubMed: 21251303]. [PubMed Central: PMC3032715].
  • 10. Boone JM, Cui W. Spectrum of bone marrow morphologic findings in hepatitis C patients with and without prior liver transplantation. Int J Lab Hematol. 2016;38(6):694-702. doi: 10.1111/ijlh.12559. [PubMed: 27572295].
  • 11. Ansuini V, Rigante D, Esposito S. Debate around infection-dependent hemophagocytic syndrome in paediatrics. BMC Infect Dis. 2013;13:15. doi: 10.1186/1471-2334-13-15. [PubMed: 23324497]. [PubMed Central: PMC3549728].
  • 12. Saxena P, Bihari C, Rastogi A, Sood V, Khanna R, Alam S, et al. Hepatitis A induced hemophagocytic syndrome. Trop Gastroenterol. 2014;35(2):122-4. doi: 10.7869/tg.195. [PubMed: 25470879].
  • 13. Rauff B, Idrees M, Shah SA, Butt S, Butt AM, Ali L, et al. Hepatitis associated aplastic anemia: A review. Virol J. 2011;8:87. doi: 10.1186/1743-422X-8-87. [PubMed: 21352606]. [PubMed Central: PMC3052191].
  • 14. Cengiz C, Turhan N, Yolcu OF, Yilmaz S. Hepatitis associated with aplastic anemia: Do CD8(+) kupffer cells have a role in the pathogenesis? Dig Dis Sci. 2007;52(9):2438-43. doi: 10.1007/s10620-006-9280-4. [PubMed: 17443406].
  • 15. Kojima S, Matsuyama K, Kodera Y, Okada J. Circulating activated suppressor T lymphocytes in hepatitis-associated aplastic anaemia. Br J Haematol. 1989;71(1):147-51. doi: 10.1111/j.1365-2141.1989.tb06289.x. [PubMed: 2521796].
  • 16. Senin A, Broquetas T, Canete N, Lens S, Londono MC, Ferraro M, et al. Aplastic anemia and severe myelosuppression with boceprevir or simeprevir-containing hepatitis C virus treatment. Ann Hepatol. 2017;16(2):312-7. doi: 10.5604/16652681.1231593. [PubMed: 28233734].

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