International Journal of Infection

Published by: Kowsar

Invasive Rhinosinusitis due to Alternaria alternata and Rhizopus arrhizus Mixed Infection: A Case Report and Review

Brijesh Sharma 1 , * , Ulka Kamble 1 , Gopal Ghosh 1 , Akhilandeswari Prasad 2 and Anuradha Chowdhary 3
Authors Information
1 Department of Medicine, Dr. RML Hospital & PGIMER, New Delhi, India
2 Department of Radiology , Dr. RML Hospital & PGIMER, New Delhi, India
3 Department of Medical Mycolgy ,Vallabh Bhai Patel Chest Institute , Institute, University Of Delhi, India
Article information
  • International Journal of Infection: October 2017, 4 (4); e42127
  • Published Online: November 13, 2016
  • Article Type: Case Report
  • Received: September 25, 2016
  • Revised: October 14, 2016
  • Accepted: October 14, 2016
  • DOI: 10.5812/iji.42127

To Cite: Sharma B, Kamble U, Ghosh G, Prasad A, Chowdhary A. Invasive Rhinosinusitis due to Alternaria alternata and Rhizopus arrhizus Mixed Infection: A Case Report and Review, Int J Infect. 2017 ; 4(4):e42127. doi: 10.5812/iji.42127.

Copyright © 2016, Infectious Diseases and Tropical Medicine Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
  • 1. Michael RC, Michael JS, Ashbee RH, Mathews MS. Mycological profile of fungal sinusitis: An audit of specimens over a 7-year period in a tertiary care hospital in Tamil Nadu. Indian J Pathol Microbiol. 2008; 51(4): 493-6[DOI][PubMed]
  • 2. Malani PN, Kauffman CA. Invasive and Allergic Fungal Sinusitis. Curr Infect Dis Rep. 2002; 4(3): 225-32[PubMed]
  • 3. Dimaka K, Mallis A, Naxakis SS, Marangos M, Papadas TA, Stathas T, et al. Chronic rhinocerebral mucormycosis: a rare case report and review of the literature. Mycoses. 2014; 57(11): 699-702[DOI][PubMed]
  • 4. Hasan HA. Phytotoxicity of pathogenic fungi and their mycotoxins to cereal seedling viability. Mycopathologia. 1999; 148(3): 149-55[DOI][PubMed]
  • 5. Li F, Yoshizawa T. Alternaria mycotoxins in weathered wheat from China. J Agric Food Chem. 2000; 48(7): 2920-4[DOI][PubMed]
  • 6. Morrison VA, McGlave PB. Mucormycosis in the BMT population. Bone Marrow Transplant. 1993; 11(5): 383-8[PubMed]
  • 7. Brandt ME, Warnock DW. Epidemiology, clinical manifestations, and therapy of infections caused by dematiaceous fungi. J Chemother. 2003; 15 Suppl 2: 36-47[DOI][PubMed]
  • 8. Gene J, Azon-Masoliver A, Guarro J, Ballester F, Pujol I, Llovera M, et al. Cutaneous phaeohyphomycosis caused by Alternaria longipes in an immunosuppressed patient. J Clin Microbiol. 1995; 33(10): 2774-6[PubMed]
  • 9. Pastor FJ, Guarro J. Alternaria infections: laboratory diagnosis and relevant clinical features. Clin Microbiol Infect. 2008; 14(8): 734-46[DOI][PubMed]
  • 10. Pereiro M, Pereiro Ferreiros MM, De Hoog GS, Toribio J. Cutaneous infection caused by Alternaria in patients receiving tacrolimus. Med Mycol. 2004; 42(3): 277-82[DOI][PubMed]
  • 11. Wiest PM, Wiese K, Jacobs MR, Morrissey AB, Abelson TI, Witt W, et al. Alternaria infection in a patient with acquired immunodeficiency syndrome: case report and review of invasive alternaria infections. Rev Infect Dis. 1987; 9(4): 799-803[DOI][PubMed]
  • 12. Gilaberte M, Bartralot R, Torres JM, Reus FS, Rodriguez V, Alomar A, et al. Cutaneous alternariosis in transplant recipients: clinicopathologic review of 9 cases. J Am Acad Dermatol. 2005; 52(4): 653-9[DOI][PubMed]
  • 13. Bartynski JM, McCaffrey TV, Frigas E. Allergic fungal sinusitis secondary to dermatiaceous fungi-Curvularia lunata and Alternaria. Otolaryngol Head Neck Surg. 1990; 103: 32-9[DOI]
  • 14. Chowdhary A, Agarwal K, Randhawa HS, Kathuria S, Gaur SN, Najafzadeh MJ, et al. A rare case of allergic bronchopulmonary mycosis caused by Alternaria alternata. Med Mycol. 2012; 50(8): 890-6[DOI][PubMed]
  • 15. Talmi YP, Goldschmied-Reouven A, Bakon M, Barshack I, Wolf M, Horowitz Z, et al. Rhino-orbital and rhino-orbito-cerebral mucormycosis. Otolaryngol Head Neck Surg. 2002; 127(1): 22-31[DOI][PubMed]
  • 16. Monroe MM, McLean M, Sautter N, Wax MK, Andersen PE, Smith TL, et al. Invasive fungal rhinosinusitis: a 15-year experience with 29 patients. Laryngoscope. 2013; 123(7): 1583-7[DOI][PubMed]
  • 17. deShazo RD, O'Brien M, Chapin K, Soto-Aguilar M, Gardner L, Swain R. A new classification and diagnostic criteria for invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg. 1997; 123(11): 1181-8[DOI][PubMed]
  • 18. El-Beltagy Y, Hamdy TAH, Hasaballah MS. Orbital complications following sinusitis still a problem: Our experience and results. Egyptian J Ear, Nose, Throat Allied Sci. 2014; 15: 189-95
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments