International Journal of Infection

Published by: Kowsar

Inhibitory Effects of Plant Extracts on Pseudomonas aeruginosa Biofilm Formation

Mohammad Amin Mashhady 1 , Javad Abkhoo 2 , Somayeh Jahani 3 , * , Sima Abyar 4 and Forozan Khosravani 4
Authors Information
1 Department of Food Industry, Faculty of Agriculture, University of Zabol, Zabol, IR Iran
2 Institute of Plant Biotechnology, Center of Agricultural Biotechnology University of Zabol, Zabol, IR Iran
3 Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran
4 Department of Horticulture and Landscape, Faculty of Agriculture, University of Zabol, Zabol, IR Iran
Article information
  • International Journal of Infection: October 01, 2016, 3 (4); e38199
  • Published Online: May 23, 2016
  • Article Type: Research Article
  • Received: April 4, 2016
  • Revised: May 4, 2016
  • Accepted: May 5, 2016
  • DOI: 10.17795/iji.38199

To Cite: Mashhady M A, Abkhoo J, Jahani S, Abyar S, Khosravani F. Inhibitory Effects of Plant Extracts on Pseudomonas aeruginosa Biofilm Formation, Int J Infect. 2016 ; 3(4):e38199. doi: 10.17795/iji.38199.

Copyright © 2016, Infectious Diseases and Tropical Medicine Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Stoodley P, Sauer K, Davies DG, Costerton JW. Biofilms as complex differentiated communities. Annu Rev Microbiol. 2002; 56: 187-209[DOI][PubMed]
  • 2. Palmer J, Flint S, Brooks J. Bacterial cell attachment, the beginning of a biofilm. J Ind Microbiol Biotechnol. 2007; 34(9): 577-88[DOI][PubMed]
  • 3. Gilbert P, Maira-Litran T, McBain AJ, Rickard AH, Whyte FW. The physiology and collective recalcitrance of microbial biofilm communities. Adv Microb Physiol. 2002; 46: 202-56[PubMed]
  • 4. Leriche V, Briandet R, Carpentier B. Ecology of mixed biofilms subjected daily to a chlorinated alkaline solution: spatial distribution of bacterial species suggests a protective effect of one species to another. Environ Microbiol. 2003; 5(1): 64-71[PubMed]
  • 5. Stoodley P, Wilson S, Hall-Stoodley L, Boyle JD, Lappin-Scott HM, Costerton JW. Growth and detachment of cell clusters from mature mixed-species biofilms. Appl Environ Microbiol. 2001; 67(12): 5608-13[DOI][PubMed]
  • 6. Shakeri S, Kermanshahi RK, Moghaddam MM, Emtiazi G. Assessment of biofilm cell removal and killing and biocide efficacy using the microtiter plate test. Biofouling. 2007; 23(1-2): 79-86[DOI][PubMed]
  • 7. Oosthuizen MC, Steyn B, Lindsay D, Brozel VS, von Holy A. Novel method for the proteomic investigation of a dairy-associated Bacillus cereus biofilm. FEMS Microbiol Lett. 2001; 194(1): 47-51[PubMed]
  • 8. Bos R, van der Mei HC, Busscher HJ. Physico-chemistry of initial microbial adhesive interactions--its mechanisms and methods for study. FEMS Microbiol Rev. 1999; 23(2): 179-230[PubMed]
  • 9. Karageorgos L, Harmatz P, Simon J, Pollard A, Clements PR, Brooks DA, et al. Mutational analysis of mucopolysaccharidosis type VI patients undergoing a trial of enzyme replacement therapy. Hum Mutat. 2004; 23(3): 229-33[DOI][PubMed]
  • 10. Anwar H, van Biesen T, Dasgupta M, Lam K, Costerton JW. Interaction of biofilm bacteria with antibiotics in a novel in vitro chemostat system. Antimicrob Agents Chemother. 1989; 33(10): 1824-6[PubMed]
  • 11. Russell NJ, Gacesa P. Chemistry and biology of the alginate of mucoid strains of Pseudomonas aeruginosa in cystic fibrosis. Mol Aspects Med. 1988; 10(1): 1-91[PubMed]
  • 12. Lari AR, Alaghehbandan R. Nosocomial infections in an Iranian burn care center. Burns. 2000; 26(8): 737-40[PubMed]
  • 13. Branda SS, Vik S, Friedman L, Kolter R. Biofilms: the matrix revisited. Trends Microbiol. 2005; 13(1): 20-6[DOI][PubMed]
  • 14. Fonseca AP, Extremina C, Fonseca AF, Sousa JC. Effect of subinhibitory concentration of piperacillin/tazobactam on Pseudomonas aeruginosa. J Med Microbiol. 2004; 53: 903-10[DOI][PubMed]
  • 15. Warren RL, Baker NR, Johnson J, Stapleton MJ. Selective inhibition of the accumulation of extracellular proteases of Pseudomonas aeruginosa by gentamicin and tobramycin. Antimicrob Agents Chemother. 1985; 27(4): 468-72[PubMed]
  • 16. Jafari S, Mobasher MA, Najafipour S, Ghasemi Y, Mobasher N, Naghizade MM, et al. Evaluation of inhibitory effects of Chlorella vulgaris extract on growth, proliferation and biofilm formation by Streptococcus mutans and evaluation of its toxicity. J Fasa Univ Med Sci. 2015; 5(3): 387-95
  • 17. Mohammadi-Sichani M, Karbasizadeh V, Dokhaharani S. Effect of Oak Galls Extracts on Streptococcus mutans Growth and Biofilm Formation. J Mazandaran Univ Med Sci. 2015; 25(121)
  • 18. Hassanshahian M, Mohsenipour Z. The antimicrobial effects of the alcoholic extracts of Pomegranate (Punica Granatum) on the Planktonic forms and biofilm structures of six pathogenic Bacteria. J Babol Univ Med Sci. 2014; 17(1): 77-84
  • 19. Mohsenipour M, Hassanshahian Z. Investigating the Effectiveness of Centaureacyanus Extracts on Planktonic Growth and Biofilm Structures of Six Pathogenic Bacteria. SSU J. 2014; 22(4): 1358-70
  • 20. Krasowska A, Sigler K. How microorganisms use hydrophobicity and what does this mean for human needs? Front Cell Infect Microbiol. 2014; 4: 112[DOI][PubMed]
  • 21. Bokaeian M, Shahraki Zahedani S, Soltanian Bajgiran M, Ansari Moghaddam A. Frequency of PER, VEB, SHV, TEM and CTX-M Genes in Resistant Strains of Pseudomonas aeruginosa Producing Extended Spectrum beta-Lactamases. Jundishapur J Microbiol. 2015; 8(1)[DOI][PubMed]
  • 22. Sederi H. The effect of pomegranate peel on pseudomonas aeruginosa biofilm formation. J Med Microbiol Iran. 2007; 1(2): 9-14
  • 23. Mohsenipour Z, Hassanshahian M. The Antimicrobial Effect of the Alcoholic Extracts of Pomegranate (Punica Granatum) on the Planktonic from and Biofilm Structures of six Pathogenic Bacteria. J Babol Univ Med Sci. 2015; 17(1)
  • 24. Zahin M, Hasan S, Aqil F, Ahmad Khan MS, Mabood Husain F, Ahmad I. Screening of certain medicinal plants from India for their anti-quorum sensing activity. Indian J Exp Biol. 2010; 48(12): 1219
  • 25. Tran PA, Webster TJ. Nanotechnology: nanofabrication, patterning, and self assembly. 2009;
  • 26. Sotiriou GA, Pratsinis SE. Antibacterial activity of nanosilver ions and particles. Environ Sci Technol. 2010; 44(14): 5649-54[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments