International Journal of Infection

Published by: Kowsar

Antibiogram of Methicillin-Resistant Staphylococcus aureus Isolates From MRSA Colonized Patients in Two Tertiary Hospital Emergency Departments

Haruaki Wakatake 1 , Shigeki Fujitani 1 , Yuka Kitano 1 , Alan T. Lefor 2 and Yasuhiko Taira 1 , *
Authors Information
1 Department of Emergency and Critical Care Medicine, St. Marianna University Hospital, Kawasaki, Japan
2 Department of Surgery, Jichi Medical University, Shimotsuke-Shi, Japan
Article information
  • International Journal of Infection: January 1, 1970, 2 (4); e32695
  • Published Online: October 28, 2015
  • Article Type: Research Article
  • Received: September 1, 2015
  • Accepted: September 2, 2015
  • DOI: 10.17795/iji-32695

To Cite: Wakatake H, Fujitani S, Kitano Y, Lefor A T, Taira Y. Antibiogram of Methicillin-Resistant Staphylococcus aureus Isolates From MRSA Colonized Patients in Two Tertiary Hospital Emergency Departments, Int J Infect. 1970 ; 2(4):e32695. doi: 10.17795/iji-32695.

Copyright © 2015, Infectious Diseases and Tropical Medicine Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Davis KA, Stewart JJ, Crouch HK, Florez CE, Hospenthal DR. Methicillin-resistant Staphylococcus aureus (MRSA) nares colonization at hospital admission and its effect on subsequent MRSA infection. Clin Infect Dis. 2004; 39(6): 776-82[DOI][PubMed]
  • 2. JANIS . Japan Nosocomial Infections Surveillance. Infection Control for Nosocomial Infections in 2011. 2011;
  • 3. Fridkin SK, Hageman J, McDougal LK, Mohammed J, Jarvis WR, Perl TM, et al. Epidemiological and microbiological characterization of infections caused by Staphylococcus aureus with reduced susceptibility to vancomycin, United States, 1997-2001. Clin Infect Dis. 2003; 36(4): 429-39[DOI][PubMed]
  • 4. CLSI. . Clinical and Laboratory Standards Institute. Performance for antimicrobial susceptibility testing. 2008;
  • 5. Hermsen ED, Hanson M, Sankaranarayanan J, Stoner JA, Florescu MC, Rupp ME. Clinical outcomes and nephrotoxicity associated with vancomycin trough concentrations during treatment of deep-seated infections. Expert Opin Drug Saf. 2010; 9(1): 9-14[DOI][PubMed]
  • 6. Soriano A, Marco F, Martinez JA, Pisos E, Almela M, Dimova VP, et al. Influence of vancomycin minimum inhibitory concentration on the treatment of methicillin-resistant Staphylococcus aureus bacteremia. Clin Infect Dis. 2008; 46(2): 193-200[DOI][PubMed]
  • 7. Hidayat LK, Hsu DI, Quist R, Shriner KA, Wong-Beringer A. High-dose vancomycin therapy for methicillin-resistant Staphylococcus aureus infections: efficacy and toxicity. Arch Intern Med. 2006; 166(19): 2138-44[DOI][PubMed]
  • 8. Lodise TP, Lomaestro B, Graves J, Drusano GL. Larger vancomycin doses (at least four grams per day) are associated with an increased incidence of nephrotoxicity. Antimicrob Agents Chemother. 2008; 52(4): 1330-6[DOI][PubMed]
  • 9. Wakatake H, Fujitani S, Kodama T, Kawamoto E, Yamada H, Yanai M, et al. Positive clinical risk factors predict a high rate of methicillin-resistant Staphylococcus aureus colonization in emergency department patients. Am J Infect Control. 2012; 40(10): 988-91[DOI][PubMed]
  • 10. Bode LG, Kluytmans JA, Wertheim HF, Bogaers D, Vandenbroucke-Grauls CM, Roosendaal R, et al. Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N Engl J Med. 2010; 362(1): 9-17[DOI][PubMed]
  • 11. CLSI. . Clinical and Laboratory Standards Institute. Performance for antimicrobial susceptibility testing. 2012;
  • 12. Colice GL, Curtis A, Deslauriers J, Heffner J, Light R, Littenberg B, et al. Medical and surgical treatment of parapneumonic effusions : an evidence-based guideline. Chest. 2000; 118(4): 1158-71[PubMed]
  • 13. Matsumoto T. Meaning of active surveillance culture for MRSA: evaluation of MRSA rapid detection by real-time PCR. Jpn Soc Environ Infect. 2009; 24
  • 14. Suzuki H, Kitaoka S. Establishment of Rational Use for Anti-MRSA Drugs and Evaluation of the Initial Dosage Setting of Vancomycin Therapy. J Jpn Soc Environ Infect. 2012; 19(3): 360-4
  • 15. Kalil AC, Murthy MH, Hermsen ED, Neto FK, Sun J, Rupp ME. Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: a systematic review and meta-analysis. Crit Care Med. 2010; 38(9): 1802-8[DOI][PubMed]
  • 16. Wunderink RG, Niederman MS, Kollef MH, Shorr AF, Kunkel MJ, Baruch A, et al. Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study. Clin Infect Dis. 2012; 54(5): 621-9[DOI][PubMed]
  • 17. Sanchez Garcia M, De la Torre MA, Morales G, Pelaez B, Tolon MJ, Domingo S, et al. Clinical outbreak of linezolid-resistant Staphylococcus aureus in an intensive care unit. JAMA. 2010; 303(22): 2260-4[DOI][PubMed]
  • 18. Moore CL, Osaki-Kiyan P, Haque NZ, Perri MB, Donabedian S, Zervos MJ. Daptomycin versus vancomycin for bloodstream infections due to methicillin-resistant Staphylococcus aureus with a high vancomycin minimum inhibitory concentration: a case-control study. Clin Infect Dis. 2012; 54(1): 51-8[DOI][PubMed]
  • 19. Kruzel MC, Lewis CT, Welsh KJ, Lewis EM, Dundas NE, Mohr JF, et al. Determination of vancomycin and daptomycin MICs by different testing methods for methicillin-resistant Staphylococcus aureus. J Clin Microbiol. 2011; 49(6): 2272-3[DOI][PubMed]
  • 20. Van Hal SJ, Lodise TP, Paterson DL. The clinical significance of vancomycin minimum inhibitory concentration in Staphylococcus aureus infections: a systematic review and meta-analysis. Clin Infect Dis. 2012; 54(6): 755-71
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