International Journal of Infection

Published by: Kowsar

Evaluation of Antibacterial Activity of Withania somnifera Leaf Extracts against Antibiotic-Resistant Isolates of Klebsiella pneumoniae

Mohammad Bokaeian 1 , Saeide Saeidi 2 , Zahra Shahi 2 , Shahla Sahraei 3 , * , Hemadollah Zarei 4 and Gelareh Sohil Baigi 5
Authors Information
1 Infectious Disease and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran
2 Department of Microbiology, Kerman Sciences and Research Branch, Islamic Azad University, Kerman, IR Iran
3 Zabol University of Medical Sciences, Zabol, IR Iran
4 Department of Plant Breeding and Biotechnology, Faculty of Agriculture, University of Zabol, Zabol, IR Iran
5 Kermanshah University of Medical Sciences, Martyr Chamran Hospital Kangavar, IR Iran
Article information
  • International Journal of Infection: July 30, 2014, 1 (2); e21085
  • Published Online: July 20, 2014
  • Article Type: Research Article
  • Received: November 10, 2013
  • Revised: February 20, 2014
  • Accepted: April 10, 2014
  • DOI: 10.17795/iji-21085

To Cite: Bokaeian M, Saeidi S, Shahi Z, Sahraei S, Zarei H, et al. Evaluation of Antibacterial Activity of Withania somnifera Leaf Extracts against Antibiotic-Resistant Isolates of Klebsiella pneumoniae, Int J Infect. 2014 ; 1(2):e21085. doi: 10.17795/iji-21085.

Abstract
Copyright © 2014, Infectious Diseases and Tropical Medicine Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
References
  • 1. Zaika LL. Spices and herbs: their antimicrobial activity and its determination1. J Food Saf. 1988; 9(2): 97-118[DOI]
  • 2. al-Hindawi MK, al-Khafaji SH, Abdul-Nabi MH. Anti-granuloma activity of Iraqi Withania somnifera. J Ethnopharmacol. 1992; 37(2): 113-6[PubMed]
  • 3. Bhattacharya SK, Satyan KS, Ghosal S. Antioxidant activity of glycowithanolides from Withania somnifera. Indian J Exp Biol. 1997; 35(3): 236-9[PubMed]
  • 4. Schliebs R, Liebmann A, Bhattacharya SK, Kumar A, Ghosal S, Bigl V. Systemic administration of defined extracts from Withania somnifera (Indian Ginseng) and Shilajit differentially affects cholinergic but not glutamatergic and GABAergic markers in rat brain. Neurochem Int. 1997; 30(2): 181-90[PubMed]
  • 5. Kulkarni SK, Ninan I. Inhibition of morphine tolerance and dependence by Withania somnifera in mice. J Ethnopharmacol. 1997; 57(3): 213-7[PubMed]
  • 6. Buchanan R. A weaver's garden. 1987; : 230-1
  • 7. Podschun R, Ullmann U. Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev. 1998; 11(4): 589-603[PubMed]
  • 8. Forbes BA, Sahm DF, Weissfeld AS. Bailey & Scott`s diagnostic microbiology. 2007; : 323-33
  • 9. M100-S16 Performance standards for antimicrobial susceptibility testing; sixteenth informational supplement. 2006;
  • 10. Saeidi S, Alavi Naini R. Antimicrobial Susceptibility and Distribution of TEM and CTX-M Genes among ESBL-producing Klebsiella pneumoniae and Pseudomonas aeruginosa Causing Urinary Tract Infections. Zahedan J Res Med Sci. 2013; 16(4): 1-5
  • 11. Zamani A, Yousefi Mashouf R, Ebrahimzadeh Namvar AM, Alikhani MY. Detection of magA Gene in Klebsiella spp. Isolated from Clinical SamplesDetection of magA. Iran J Basic Med Sci. 2013; 16(2): 173-6[PubMed]
  • 12. Singh V, Verma O. Ocimum sanctum (tulsi): Bio-pharmacological activities. Webmed Cent Pharmacol. 2010; 1(10)
  • 13. Singariya P, Kumar P, Mourya KK. Evolution of Antimicrobial Activity of Leaf extracts of Winter Cheery (Withania somnifera). Int J Pharm Res. 2012; 4(3): 1247-53
  • 14. Jaina P, Varshney R. Antimicrobial activity of aqueous and methanolic extracts of Withania somnifera (Ashwagandha). J Chem Pharm Res. 2011; 3(3): 260-3
  • 15. Singh. G , Sharma. M , Kumar. A , Verma. S , Goel. D. . Preliminary phytochemical analysis and screening of potential antibacterial activity of plant extracts against pathogenial strains of nocardia asteroids and Stereptococcus pyogenes. Int J Pharm Res Biosci. 2013; 2(5): 100-7
  • 16. Elbashiti TA, Elmanama AA, Masad AA. The antibacterial and synergistic effects of some Palestinian plant extracts on Escherichia coli and Staphylococcus aureus. Funct Plant Sci Biotechnol. 2011; 5: 57-62
  • 17. Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol. 1998; 62(3): 209-14[PubMed]
  • 18. Arora S, Dhillon S, Rani G, Nagpal A. The in vitro antibacterial/synergistic activities of Withania somnifera extracts. Fitoterapia. 2004; 75(3-4): 385-8[DOI][PubMed]
  • 19. Halamova K, Kokoska L, Polesny Z, Macakova K, Flesar J, Rada V. Selective in vitro growth inhibitory effect of Withania somnifera on human pathogenic bacteria and bifido bacteria. Pak J Bot. 2013; 45(2): 667-70
  • 20. Cushnie TP, Lamb AJ. Antimicrobial activity of flavonoids. Int J Antimicrob Agents. 2005; 26(5): 343-56[PubMed]
  • 21. Kandil FE, El Sayed NH, Abou Douh AM, Ishak MS, Mabry TJ. Flavonol glycosides and phenolics from Withania somnifera. Phytochem. 1994; 37(4): 1215-6[DOI]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments