International Journal of Infection

Published by: Kowsar

Helicobacter pylori Treatment: Potential for Gastric Cancer Prevention

Mostafa Ibrahimi 1 , Maryam Alaei 1 , Mohammad-Ali Gholampour 2 and Milad Mohammdoo-Khorasani 1 , *
Authors Information
1 Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
2 Department of Hematology and Blood Banking, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Article information
  • International Journal of Infection: April 2018, 5 (2); e14138
  • Published Online: June 6, 2017
  • Article Type: Letter
  • Received: January 7, 2017
  • Accepted: January 14, 2017
  • DOI: 10.5812/iji.14138

To Cite: Ibrahimi M, Alaei M, Gholampour M, Mohammdoo-Khorasani M. Helicobacter pylori Treatment: Potential for Gastric Cancer Prevention, Int J Infect. 2018 ; 5(2):e14138. doi: 10.5812/iji.14138.

Copyright © 2017, International Journal of Infection. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
  • 1. Malfertheiner P, Megraud F, O'Morain CA, Atherton J, Axon AT, Bazzoli F, et al. Management of Helicobacter pylori infection--the Maastricht IV/ Florence Consensus Report. Gut. 2012;61(5):646-64. doi: 10.1136/gutjnl-2012-302084. [PubMed: 22491499].
  • 2. Mentis A, Lehours P, Megraud F. Epidemiology and Diagnosis of Helicobacter pylori infection. Helicobacter. 2015;20 Suppl 1:1-7. doi: 10.1111/hel.12250. [PubMed: 26372818].
  • 3. Laird-Fick HS, Saini S, Hillard JR. Gastric adenocarcinoma: the role of Helicobacter pylori in pathogenesis and prevention efforts. Postgraduate Med J. 2016.
  • 4. Wroblewski LE, Peek RM, Coburn LA. The Role of the Microbiome in Gastrointestinal Cancer. Gastroenterol Clin North Am. 2016;45(3):543-56. doi: 10.1016/j.gtc.2016.04.010. [PubMed: 27546848].
  • 5. Hoed CM, Kuipers EJ. Gastric Cancer: How Can We Reduce the Incidence of this Disease? Current gastroenterology reports. 2016;18(7):1-8.
  • 6. Lauren P. The Two Histological Main Types of Gastric Carcinoma: Diffuse and So-Called Intestinal-Type Carcinoma. An Attempt at a Histo-Clinical Classification. Acta Pathol Microbiol Scand. 1965;64:31-49. [PubMed: 14320675].
  • 7. Plummer M, Franceschi S, Vignat J, Forman D, de Martel C. Global burden of gastric cancer attributable to Helicobacter pylori. Int J Cancer. 2015;136(2):487-90. doi: 10.1002/ijc.28999. [PubMed: 24889903].
  • 8. Venerito M, Selgrad M, Malfertheiner P. Helicobacter pylori: gastric cancer and extragastric malignancies - clinical aspects. Helicobacter. 2013;18 Suppl 1:39-43. doi: 10.1111/hel.12078. [PubMed: 24011244].
  • 9. Amieva M, Peek RM. Pathobiology of Helicobacter pylori-Induced Gastric Cancer. Gastroenterology. 2016;150(1):64-78. doi: 10.1053/j.gastro.2015.09.004. [PubMed: 26385073].
  • 10. Cover TL, Blanke SR. Helicobacter pylori VacA, a paradigm for toxin multifunctionality. Nat Rev Microbiol. 2005;3(4):320-32. doi: 10.1038/nrmicro1095. [PubMed: 15759043].
  • 11. Ding SZ, Zheng PY. Helicobacter pylori infection induced gastric cancer; advance in gastric stem cell research and the remaining challenges. Gut Pathog. 2012;4(1):18. doi: 10.1186/1757-4749-4-18. [PubMed: 23217022].
  • 12. Ford AC, Forman D, Hunt RH, Yuan Y, Moayyedi P. Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials. BMJ. 2014;348:g3174. doi: 10.1136/bmj.g3174. [PubMed: 24846275].
  • 13. Ford AC, Forman D, Hunt R, Yuan Y, Moayyedi P. Helicobacter pylori eradication for the prevention of gastric neoplasia. Cochrane Database Syst Rev. 2015;(7). CD005583. doi: 10.1002/14651858.CD005583.pub2. [PubMed: 26198377].
  • 14. Malekzadeh R, Derakhshan MH, Malekzadeh Z. Gastric cancer in Iran: epidemiology and risk factors. Arch Iran Med. 2009;12(6):576-83. [PubMed: 19877751].
  • 15. Naeimehossadat A, Tohid J, Seyyed MT. Area-to-area poisson kriging and spatial bayesian analysis in mapping of gastric cancer incidence in Iran. APJCP. 2016;17(10):4587.

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments